Molecular Markers of Ischemic Stroke

Biochemical markers in acute ischemic stroke.

Vitamin D and Ischemic Stroke

Introduction: stroke is the most important brain disease. Stroke leads to a reduction in bone density, altered calcium homeostasis, and an increase in hip fractures. Some recent studies show effects of vitamin D on stroke and vice versa. The purpose of this study was to determine of serum vitamin D levels in patients with acute stroke. Methods: In this cross-sectional study, we compared t...

dysphagia in acute ischemic stroke

Introduction: Swallowing dysfunction complicates acute strokes in 25-32% of cases and directly affects patientschr('39') prognosis and recovery. Dysphagia complicates the course of acute strokes through its potential of the development of chest infection, nutritional problems, and dehydration.  Dysphagia is also an independent predictor of respiratory morbidity and mortality in acute stroke. In...

Markers of a hypercoagulable state following acute ischemic stroke.

BACKGROUND AND PURPOSE The nature of hematologic disorders in different stroke subtypes remains uncertain. The purpose of this study was to clarify the differences in the coagulation and fibrinolytic activities among ischemic stroke subtypes. METHODS We performed sequential measurements of hematologic parameters in 21 patients with acute cardioembolic stroke, 10 patients with atherothrombotic...

Course of platelet activation markers after ischemic stroke.

BACKGROUND AND PURPOSE The aim of this study was to evaluate the time course of platelet activation after ischemic stroke and to investigate whether platelet activation and inflammation are correlated with each other. METHODS We serially determined expression of p-selectin (CD62p) and lysosome-associated membrane protein (CD63) by platelets using flow cytometry at 10 time points between days ...